The Clydeside Expressway and much of Finnieston will see many major closures beginning today.
COP26 will take place at the SEC and run from October 31 to November 12, although road closures for the UN conference in Glasgow are already well underway.
The full closure of the Clydeside Expressway begins at 9pm tonight, October 23.
Motorists and residents alike will be keen to know that the major west end route will be closed for over three weeks until it reopens Monday November 15 at 6am.
Finnieston will also see the full closure of streets near the SEC with local access only beginning tonight.
Finnieston Street between Houldsworth Streeet and West Greenhill Place will close from 9pm today to 6am on Monday November 12.
Running on a staggered closure, Finnieston Street between West Greenhill Place and Lancefield Quay will close with local access only from 9pm tonight to 6am Monday November 12.
However, that area will be fully closed from midnight Thursday, October 28 to 6am Monday, November 12.
Road closures in Finnieston started from October 10 in anticipation of the massive conference.
Get Ready Glasgow, a campaign by Glasgow City Council, explained the closures were necessary for the safety of COP26, which will see the arrival of 30,000 attendees.
It stated: “These measures are needed to facilitate the safe delivery of the event and maintain the safety and security of participants, citizens and visitors.”
Alternate routes for the many closures in the west end include Argyle Street, Dumbarton Road, Byres Road, Great Western Road, University Avenue and Gibson Street.
Crow Road is the furthest west end alternate route.