Despite a Mats Hummels own goal costing them against France in a 1-0 defeat to open their tournament, the Germans were solid in defence – but the attack was toothless in Munich versus the world champions.
Low, in his last tournament in charge, is unlikely to tinker with his three-man backline, but could make changes further forward. Playing with Serge Gnabry in a forward role and Kai Havertz and Thomas Mueller on the wings did not work, and Timo Werner is an option with his pace on the flanks.
As for Portugal, Cristiano Ronaldo found the net twice in a 3-0 late show against Hungary, and they are likely to look much the same this time around.
Here is how we think the two sides will line up…
Portugal vs Germany predicted lineups
Portugal XI: Rui Patricio; Nelson Semedo, Ruben Dias, Pepe, Guerreiro; Danilo, William Carvalho; Diogo Jota, Bruno Fernandes, Bernardo Silva; Ronaldo
Germany XI: Neuer; Ginter, Hummels, Rudiger; Kimmich, Gundogan, Kroos, Gosens; Havertz, Muller; Gnabry
Portugal vs Germany squads
Goalkeepers: Anthony Lopes, Rui Patrício, Rui Silva
Defenders: Diogo Dalot, Nelson Semedo, Jose Fonte, Pepe, Ruben Dias, Nuno Mendes, Raphael Guerreiro
Midfielders: Danilo Pereira, Joao Palhinha, Ruben Neves, Bruno Fernandes, Joao Moutinho, Renato Sanches, Sergio Oliveira, William Carvalho
Forwards: Pedro Goncalves, Andre Silva, Bernardo Silva, Cristiano Ronaldo, Diogo Jota, Goncalo Guedes, Joao Felix, Rafa Silva
Goalkeepers: Bernd Leno, Manuel Neuer, Kevin Trapp
Defenders: Matthias Ginter, Robin Gosens, Christian Gunter, Marcel Halstenberg, Mats Hummels, Lukas Klostermann, Robin Koch, Antonio Rudiger, Niklas Sule
Midfielders: Emre Can, Leon Goretzka, Ilkay Gundogan, Kai Havertz, Jonas Hofmann, Joshua Kimmich, Toni Kroos, Florian Neuhaus
Forwards: Serge Gnabry, Thomas Muller, Jamal Musiala, Timo Werner, Leroy Sane, Kevin Kolland