Three people have died after the fast-moving vehicle they were in hit a block of flats.
The car hit a residential block in Great Western Road, near the junction with Harrow Road, Westminster at 4.50am today.
Police, London Fire Brigade and London Ambulance Service paramedics attended the scene but found the vehicle in flames.
Fire crews extinguished the blaze but, despite the best efforts of emergency services, three people were pronounced dead at the scene.
Work to identify the deceased and inform their next of kin is ongoing.
There are not believed to be any other injuries and at this stage no other vehicles are believed to have been involved.
Detectives from the Serious Collision Investigation Unit are appealing for witnesses and those with dash cam footage to come forward following the incident.
A number of residents were evacuated from the building as a precaution.
A London Fire Brigade spokesperson said: “Firefighters were called to reports a car had collided with a sheltered accommodation block. The vehicle was alight when crews arrived.
“Crews tackled the fire and led nine people to safety from the block via an internal staircase.
“Three people in the vehicle were sadly pronounced dead at the scene.”
Police officers have set up a cordon blocking off either side of Great Western Road.
Six officers are on the scene to redirect pedestrians and traffic. The cordon at the junction of Harrow Road and Great Western Road is expected to be in place for several hours.
A scene remains in place and enquiries are ongoing.
Anyone who saw the car before the incident, or who has information, video or images that could help police, is urged to call 101 ref CAD 917/14 Sept.
Anyone with information can call police on 101 quoting the reference CAD 917/14 Sept.